Toward the end of the play Freud’s Last Session, a fictional conversation about the meaning of human life between Sigmund Freud and C.S. Lewis concludes, “How mad, to think we could untangle the world’s greatest mystery in one hour.” Freud responds, “The only thing more mad is to not think of it at all.” The combined sense of the limits to human knowledge and the unavoidability of the big questions is one of the many impressive features of this dramatic production, the remote origins of which are in a popular class of Dr. Armand Nicholi, professor of psychiatry in the Harvard Medical School. Nicholi penned a book, The Question of God: C.S. Lewis and Sigmund Freud Debate God, Love, Sex, and the Meaning of Life, which the playwright Mark St. Germain turned into an off-Broadway play, now in its second year in New York and just beginning a run in Chicago.